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Validazione input MM-MRD
done
Rilevati 10 file FCS
Creato: 2026-04-03 17:53:09
Avvio: 2026-04-03 17:53:09 · Fine: 2026-04-03 17:53:21
Runner backend: Wrapper completo
Messaggio: Completato
/opt/cbflow/venv/bin/python /opt/cbflow/backend/flowct_py_v2_project/scripts/run_mm_mrd_pipeline.py --input-dir /opt/cbflow/backend/flowct_py_v2_project/web_mpv/job_runs/20260403_175309_b6ba5cd7/inputs --metadata-csv /opt/cbflow/backend/flowct_py_v2_project/web_mpv/job_runs/20260403_175309_b6ba5cd7/inputs/sample_metadata.csv --output-dir /opt/cbflow/backend/flowct_py_v2_project/web_mpv/job_runs/20260403_175309_b6ba5cd7/outputs
Campi chiave del report MM-MRD, inclusa la distinzione tra call standard T2 e rescued T2.
| Case | Patient | Final clonality | Clonality source | Standard T2 call | Rescued T2 call | Rescue subset n | MRD burden | MRD status | Hemodilution | anti-CD38 flag | sample_type | analysis_mode | engine_mode | panel_id | panel_supported | anti_cd38_safe | events_total | events_analyzed | event_qc_flag | total_pc_count | normal_pc_count | aberrant_pc_count | uncertain_pc_count | mrd_burden | lod | loq | research_only_flag | warnings |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MMMRD_P01 | MMMRD_P01 | polyclonal_or_non_informative | unresolved | polyclonal_or_non_informative | not_attempted | 0 | 0.00e+00 | not_detected | adequate | no | BM | mm_mrd | real_gating_v1_3 | ngf_inspired_2t_8c | yes | yes | 150000 | 149402 | insufficient | 4505 | 4488 | 0 | 17 | 0.0 | 0.00013386701650580312 | 0.00033466754126450785 | yes | Real gating v1.3 active: rule-based plasma-cell gating, sample-adaptive aberrancy scoring, and robust T2 clonality rescue. | Current v1 uses independent T1 and T2 compartment logic; no advanced multi-tube cell-by-cell fusion yet. | Clonality not confidently resolved on T2 with current v1.3 thresholds. | Low-count non-clonal aberrant-like events were suppressed by the v1.1 noise floor. |
| MMMRD_P02 | MMMRD_P02 | kappa_restricted | standard_t2 | kappa_restricted | not_needed | 0 | 1.00e-04 | trace_below_lod | adequate | no | BM | mm_mrd | real_gating_v1_3 | ngf_inspired_2t_8c | yes | yes | 150000 | 149402 | insufficient | 4520 | 4492 | 15 | 13 | 0.00010040026237935235 | 0.00013386701650580312 | 0.00033466754126450785 | yes | Real gating v1.3 active: rule-based plasma-cell gating, sample-adaptive aberrancy scoring, and robust T2 clonality rescue. | Current v1 uses independent T1 and T2 compartment logic; no advanced multi-tube cell-by-cell fusion yet. |
| MMMRD_P03 | MMMRD_P03 | lambda_restricted | standard_t2 | lambda_restricted | not_needed | 0 | 6.89e-04 | quantifiable | adequate | no | BM | mm_mrd | real_gating_v1_3 | ngf_inspired_2t_8c | yes | yes | 150000 | 149401 | insufficient | 4651 | 4516 | 103 | 32 | 0.0006894197495331357 | 0.00013386791253070594 | 0.0003346697813267649 | yes | Real gating v1.3 active: rule-based plasma-cell gating, sample-adaptive aberrancy scoring, and robust T2 clonality rescue. | Current v1 uses independent T1 and T2 compartment logic; no advanced multi-tube cell-by-cell fusion yet. |
| MMMRD_P04 | MMMRD_P04 | kappa_restricted | rescued_t2 | polyclonal_or_non_informative | kappa_restricted | 3 | 4.69e-05 | trace_below_lod | suboptimal_hemodiluted | no | BM | mm_mrd | real_gating_v1_3 | ngf_inspired_2t_8c | yes | yes | 150000 | 149401 | insufficient | 2834 | 2749 | 7 | 78 | 4.685376938574708e-05 | 0.00013386791253070594 | 0.0003346697813267649 | yes | Real gating v1.3 active: rule-based plasma-cell gating, sample-adaptive aberrancy scoring, and robust T2 clonality rescue. | Current v1 uses independent T1 and T2 compartment logic; no advanced multi-tube cell-by-cell fusion yet. | T2 clonality rescue accepted on a high-stringency subset (n=3, dominance=1.00). | Hemodilution-aware stricter aberrancy threshold applied (score >= 4). |
| MMMRD_P05 | MMMRD_P05 | kappa_restricted | standard_t2 | kappa_restricted | not_needed | 0 | 3.95e-04 | quantifiable | adequate | possible | BM | mm_mrd | real_gating_v1_3 | ngf_inspired_2t_8c | yes | conditional | 150000 | 149401 | insufficient | 4557 | 4485 | 59 | 13 | 0.0003949103419655826 | 0.00013386791253070594 | 0.0003346697813267649 | yes | Possible anti-CD38 interference: use CD138/multiparametric fallback, not CD38 alone | Real gating v1.3 active: rule-based plasma-cell gating, sample-adaptive aberrancy scoring, and robust T2 clonality rescue. | Current v1 uses independent T1 and T2 compartment logic; no advanced multi-tube cell-by-cell fusion yet. |
I file vengono raggruppati per estensione per facilitare il download.
$ /opt/cbflow/venv/bin/python /opt/cbflow/backend/flowct_py_v2_project/scripts/run_mm_mrd_pipeline.py --input-dir /opt/cbflow/backend/flowct_py_v2_project/web_mpv/job_runs/20260403_175309_b6ba5cd7/inputs --metadata-csv /opt/cbflow/backend/flowct_py_v2_project/web_mpv/job_runs/20260403_175309_b6ba5cd7/inputs/sample_metadata.csv --output-dir /opt/cbflow/backend/flowct_py_v2_project/web_mpv/job_runs/20260403_175309_b6ba5cd7/outputs Wrote 5 case summaries to /opt/cbflow/backend/flowct_py_v2_project/web_mpv/job_runs/20260403_175309_b6ba5cd7/outputs